Pyrimidines And Derivatives
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Filtered Search Results
Aobchem AOBCHEM
5001034845 1-BENZO B THIEN-7-YLETHANONE 5
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Aobchem AOBCHEM
5001035099 1-BENZO B THIEN-7-YLETHANONE 1
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Aobchem AOBCHEM
5001036886 1-BENZO B THIEN-7-YLETHANONE 2
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Aobchem AOBCHEM
5001037665 2- BENZYLOXY PYRIMIDIN-5-OL 25
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Aobchem AOBCHEM
5001038083 2- DIETHYLAMINO PYRIMIDIN-5-Y
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eMolecules 271-70-5 | 1H-Pyrrolo[2,3-d]pyrimidine | Synthonix - Stock | MFCD08234403 | 119.127 | C6H5N3 | 97.000 | c1cc2cncnc2[nH]1 | 1g | 525922383
1H-Pyrrolo[2,3-d]pyrimidine | Synthonix - Stock | 271-70-5 | MFCD08234403 | 119.127 | C6H5N3 | 97.000 | c1cc2cncnc2[nH]1 | 1g | 525922383
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eMolecules 271-70-5 | 7H-Pyrrolo[2,3-d]pyrimidine | Ambeed | MFCD08234403 | 119.127 | C6H5N3 | 98.000 | c1cc2cncnc2[nH]1 | 25g | 552592026
7H-Pyrrolo[2,3-d]pyrimidine | Ambeed | 271-70-5 | MFCD08234403 | 119.127 | C6H5N3 | 98.000 | c1cc2cncnc2[nH]1 | 25g | 552592026
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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eMolecules 51953-18-5 | Pyrimidin-4-ol | Ambeed | MFCD00038024 | 96.089 | C4H4N2O | 97.000 | Oc1ccncn1 | 25g | 552570889
Pyrimidin-4-ol | Ambeed | 51953-18-5 | MFCD00038024 | 96.089 | C4H4N2O | 97.000 | Oc1ccncn1 | 25g | 552570889
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Medchemexpress LLC WYE-687 | 1062161-90-3 | C28H32N8O3 | 5 MG
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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WYE-687 is an ATP-competitive mTOR inhibitor with an IC50 of 7 nM. It concurrently inhibits the activation of mTORC1 and mTORC2. WYE-687 also inhibits PI3Kα and PI3Kγ with IC50s of 81 nM and 3.11 μM, respectively.
- ATP-competitive mTOR inhibitor
- Inhibits activation of mTORC1 and mTORC2
- Inhibits PI3Kα and PI3Kγ
- Potently inhibits HL-60 cell survival
- Cytotoxic to U937, THP-1 and AML-193 AML cell lines
- Significantly inhibits U937 xenograft tumor growth in SCID mice
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Ambeed AMBEED
5000847184 2- METHYLTHIO PYRIMIDIN 100MG
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Ambeed AMBEED
5000895178 3-BROMOTHIENO32-CPYRIDIN 250MG
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Ambeed AMBEED
5000893972 2-METHYLSULFANYL-PYRIMIDIN 1GR
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Ambeed AMBEED
5000895331 TIDEGLUSIB 250MG
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Ambeed AMBEED
5000885185 ETHYL 2-OXOCYCLOHEXANECA 100G
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Ambeed AMBEED
5000885196 ETHYL 2-4-METHOXYBENZYLA 5G
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